Understanding
Okur-Chung Neurodevelopmental Syndrome
Project: Deep Molecular Profiling of Mouse Models of OCNDS
Contract Awarded to: Unravel Biosciences, Inc.
Unravel Biosciences is a biotechnology company dedicated to unraveling the molecular underpinnings of diseases and identifying therapeutic opportunities based on computational analysis of gene expression profiles.
Grant Details:
Project funded in 2023 for 1 year in 2023.
Aims of Grant:
The CSKN2A1 Foundation has contracted Unravel Biosciences to utilize their computational platform to identify molecular differences in OCNDS mouse and human samples and compare them to individuals without OCNDS. Furthermore, Unravel will leverage their drug screening platform to identify potential therapeutics predicted to be functional within and across mouse and human models of OCNDS. After identification, collaborators in the Rebholz lab at the Institute of Psychiatry and Neuroscience of Paris will test potential therapies in various OCNDS models.