Understanding
Okur-Chung Neurodevelopmental Syndrome
Project: Development of Two OCNDS Mouse Models
Contract Awarded to: Taconic Biosciences
Taconic Biosciences is a biotechnology company specializing in the development and distribution of genetically engineered animal models.
Grant Details:
Projected funded for 3 years starting in 2021 for $35,154.
Aims of Grant:
The CSNK2A1 Foundation has contracted Taconic Biosciences to genetically engineer two mouse models of OCNDS using CRISPR-Cas9 gene-editing technology. Upon development, these mice will be available for use by outside researchers and will serve as an invaluable resource for identifying the molecular underpinnings of OCNDS and eventually developing treatments. The two OCNDS variants represented in these models are R47G and R312W.